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1.
近年来,随着抗生素的使用受限,丁酸及丁酸盐在畜牧生产中的应用越来越广泛。饲料中添加丁酸盐可提高动物生产性能、改善肠道微生态平衡和促进肠道健康发育。在肉鸡生产中,需根据品种、生长阶段以及产品特点等合理使用丁酸。文章就丁酸及丁酸盐的生物学功能及其在肉鸡生产中的应用作一综述。  相似文献   

2.
丁酸梭菌作为一种新型微生态制剂,具有耐热、耐酸、耐受多种抗生素等特点。在畜禽生产中添加丁酸梭菌制剂,不仅可促进动物生长,调节肠道菌群微生态平衡,对宿主产生多种益生作用,还可减少饲料中抗生素产品的使用,进而减少药物在肉品中的残留。使用丁酸梭菌可以降低细菌的耐药性,从而保障动物机体健康。本文主要就丁酸梭菌的生物学功能及其在动物生产中的应用进行综述,旨在为丁酸梭菌在动物健康养殖与安全生产中的应用提供参考。  相似文献   

3.
丁酸有促进幼龄反刍动物胃肠道发育、降低腹泻、缓解断奶应激和提高生长性能等生理功能。丁酸产品是在乳和饲料中添加的一类安全、无残留、环保的饲料添加剂。本文总结了丁酸在幼龄反刍动物中的作用机理,并以丁酸产品在乳和饲料中添加的应用效果为框架,综述了国内外丁酸产品在幼龄反刍动物中应用的研究进展,旨在为丁酸产品的推广应用提供参考。  相似文献   

4.
王彦丽 《养猪》2022,(5):23-26
丁酸梭菌是从健康人和动物肠道中分离出来的一种厌氧的革兰氏阳性芽孢杆菌,能分泌丁酸、消化酶和维生素等益生物质,具有耐高温、耐酸、耐高压、稳定性强、安全、高效、无残留、无污染等优点。众多研究表明,丁酸梭菌在养猪生产中可提高猪只生产性能、改善机体肠道功能、提高机体抗氧化功能与免疫性能,是一种具有广阔发展前景的新型绿色饲料添加剂。文章主要阐述丁酸梭菌的特点及其在养猪生产中的应用,为养猪场户在日常生产中更好地了解并应用丁酸梭菌提供参考。  相似文献   

5.
丁酸梭菌具有益生特性,在医药食品领域已有成功应用。丁酸梭菌作为微生物饲料添加剂在畜禽生产中的应用尚处于发展初期阶段,其作用机制的研究和应用开发相对于其他益生菌较为滞后。试验介绍丁酸梭菌的生物学功效,综述丁酸梭菌近年来在畜牧生产中的应用效果及机制研究。  相似文献   

6.
丁酸梭菌作为一种益生菌,存在于人和动物的肠道中,不易受到胃酸、消化酶和胆汁酸等因素的影响,不仅可以通过把营养物质降解成丁酸为动物提供营养与能量,而且可以保护肠道健康,促进营养物质的吸收和动物的生长,以及增强免疫功能等,因此丁酸梭菌可以作为饲料添加剂用于畜禽生产。本文对丁酸梭菌对家禽生理、生产性能的影响及其机制进行综述,以便为丁酸梭菌在家禽生产中的应用提供参考。  相似文献   

7.
饲用微生态制剂丁酸梭菌的研究与应用进展   总被引:1,自引:0,他引:1  
丁酸梭菌作为一种新型微生态制剂,具有耐热、耐酸及耐受多种抗生素等特点。在畜禽饲料中添加饲用丁酸梭菌制剂,对于减少当前饲料中抗生素产品的滥用、减少药物在肉品中的残留、降低动物细菌的耐药性和保障动物健康有着重要的意义。文章综述丁酸梭菌的生物学特性、生物学功效、丁酸梭菌制剂的培养与发酵生产工艺、饲用丁酸梭菌制剂的实际应用效果、存在问题及发展前景等几个方面的研究与应用进展。  相似文献   

8.
正肠道健康对于高产动物发挥其遗传上的生长潜力必不可少。丁酸因其会对动物肠道健康和发育产生有益作用而闻名。如今,多种以丁酸为主要成分的产品已经上市。以α-单丁酸甘油酯和三丁酸甘油酯形式的丁酸甘油酯混合物已显示出能够改善断奶仔猪生产性能的作用。  相似文献   

9.
正丁酸梭菌又名丁酸菌、酪酸梭菌,细菌学分类属于梭菌属,是从人和动物肠道中分离出的一种厌氧型革兰氏阳性芽孢杆菌,能在动物肠道内定植,并产生丁酸和乳酸等短链脂肪酸为主要益生产物的益生菌。丁酸梭菌作为新一代芽孢益生菌制剂,具有耐热、耐酸和耐多种抗生素等生物学特性。在畜禽生产中添加丁酸梭菌制剂,不仅可促进动物生长,调节肠道菌群微生态平衡,还可减少饲料中抗生素产品的使用,进而减少药物在肉品中的残留,  相似文献   

10.
试验对三丁酸甘油酯的合成、检测以及微囊化工艺进行探讨优化。从合成的物料比例、催化剂种类、搅拌方式和速度方面进行相关试验,产物通过气相色谱(GC)检测,采用热喷制粒的方式对产品进行微囊化。结果显示:甘油和丁酸的物质的量的比为1∶4,固体催化剂用量为0.1%,锚式搅拌,转速800 r/min为最优合成条件。研究表明,优化方法生产的三丁酸甘油酯无色透明,含量高达95%,且微胶囊粉的颗粒均一、包埋率高,有助于扩展产品的应用范围。  相似文献   

11.
1-(2-Chloroethyl)3-cyclohexyl-1-nitrosourea (CCNU) is an alkylating agent in the nitrosourea subclass. A prospective evaluation of CCNU was done to determine the maximally tolerated dosage of CCNU in tumor-bearing cats. Response data were obtained when available. Twenty-five cats were treated with CCNU at a dosage of 50-60 mg/m3 body surface area. Complete hematologic data were available for 13 cats. Neutropenia was the acute dose-limiting toxicity. The median neutrophil count at the nadir was 1,000 cells/microL (mean, 2,433 cells/microL; range, 0-9,694 cells/microL). The time of neutrophil nadir was variable, occurring 7-28 days after treatment, and counts sometimes did not return to normal for up to 14 days after the nadir. Based on these findings, a 6-week dosing interval and weekly hematologic monitoring after the 1st treatment with CCNU are recommended. The nadir of the platelet count may occur 14-21 days after treatment. The median platelet count at the nadir was 43,500 cells/microL. No gastrointestinal, renal, or hepatic toxicities were observed after a single CCNU treatment, and additional studies to evaluate the potential for cumulative toxicity should be performed. Five cats with lymphoma and 1 cat with mast cell tumor had measurable responses to CCNU. Phase II studies to evaluate antitumor activity should be completed with a dosing regimen of 50-60 mg/m3 every 6 weeks.  相似文献   

12.
Human and equine athletes are reported to have a high prevalence of gastric disease, and anecdotal evidence suggests a similar phenomenon applies to racing sled dogs. To investigate the prevalence of gastric disease in racing sled dogs, we conducted 2 gastroscopy studies on dogs competing in the annual Iditarod Sled Dog Race. A pilot study of dogs that were either dropped from the 2000 Iditarod Sled Dog Race because of illness or that finished the race indicated that, approximately 5 days after competing, 10 of 28 dogs (35%) had endoscopic evidence of gastric ulceration, erosion, or hemorrhage. The next year, an endoscopic study of 73 dogs participating in the 2001 Iditarod race was performed in order to evaluate a larger population of dogs. Data from 70 of these dogs could be used; 34 (48.5%) had ulceration, erosion, gastric hemorrhage, or some combination of these findings. When this group of 70 dogs was compared retrospectively to a control group of 87 dogs presented to the Texas A&M University (TAMU) Veterinary Medical Teaching Hospital, the Iditarod sled dogs had a significantly higher prevalence (P = .049) of gastric lesions. These findings suggest that, similar to athletes of other species, elite canine athletes have an increased prevalence of gastric disease compared to the canine population at large.  相似文献   

13.
Continuous rate infusion (CRI) of furosemide in humans is considered superior to intermittent administration (IA). This study examined whether furosemide CRI, compared with IA, would increase diuretic efficacy with decreased fluid and electrolyte fluctuations and activation of the renin-angiotensin-aldosterone system (RAAS) in the horse. Five mares were used in a crossover-design study. During a 24-hour period, each horse received a total of 3 mg/kg furosemide by either CRI (0.12 mg/kg/h preceded by a loading dose of 0.12 mg/kg IV) or IA (1 mg/kg IV q8h). There was not a statistically significant difference in urine volume over 24 hours between methods; however, urine volume was significantly greater after CRI compared with IA during the first 8 hours ([median 25th percentile, 75th percentile]: 9.6 L [8.9, 14.4] for CRI versus 5.9 L [5.3, 6.0] for IA). CRI produced a more uniform urine flow, decreased fluctuations in plasma volume, and suppressed renal concentrating ability throughout the infusion period. Potassium, Ca, and Cl excretion was greater during CRI than IA (1,133 mmol [1.110, 1,229] versus 764 mmol [709, 904], 102.7 mmol [96.0, 117.2] versus 73.3 mmol [65.0, 73.5], and 1,776 mmol [1,657, 2.378] versus 1,596 mmol [1,457, 1,767], respectively). Elimination half-lives of furosemide were 1.35 and 0.47 hours for CRI and IA, respectively. The area under the excretion rate curve was 1,285.7 and 184.2 mL x mg/mL for CRI and IA, respectively. Furosemide CRI (0.12 mg/kg/h) for 8 hours, preceded by a loading dose (0.12 mg/kg), is recommended when profound diuresis is needed acutely in horses.  相似文献   

14.
15.
The epidemiology of H. placei and of other gastrointestinal nematodes in yearling dairy cattle was examined on two farms in Kiambu District, central Kenya during each of 13 one-month periods from April 1993 to April 1994. On each farm, 32 newly weaned dairy calves were given a single dose of albendazole and then placed on experimental pastures. Twelve of the animals were designated for bi-monthly slaughter (n = 2) and analysis of worm population characteristics and 20 were designated for blood and faecal collection and for weighing. Two parasite-free tracer calves were grazed alongside the weaner calves each month throughout the study period and were also slaughtered for analysis of worm populations. Faecal egg counts, haematological and serum pepsinogen determinations, herbage larval counts, and animal live weight changes were recorded monthly. The study revealed that Haemonchus placei, Trichostrongylus axei, Cooperia spp. and Oesophagostomum radiatum were responsible for parasitic gastroenteritis and that H. placei was the predominant nematode present in the young cattle on both farms. Faecal egg counts from resident cattle and necropsy worm counts revealed that pasture larval levels were directly related to the amount of rainfall. The total worm burdens in the animals were highest during the rainy season (March–June and October–December) and lowest during the dry seasons (July–September and January–February). The very low recovery of immature larvae of H. placei from the tracer calves indicated that arrested development is not a feature of the life cycle of this parasite in central Kenya. The maintenance of the parasite population depended on continuous cycling of infection between the host and the pasture. The agroclimatic conditions of the study area were such that, in general, favourable weather conditions for the development and survival of the free-living stages of gastrointestinal nematodes existed all year round.  相似文献   

16.
The occurrence of ectoparasites in sheep flocks is frequently reported but seldom quantified. Sheep production used to be a predominantly family activity in the state of Sa~o Paulo (Brazil), but it began to become a commercial activity in the past decade. Thus, information about the ectoparasites existing in sheep flocks has become necessary. The present data were obtained by means of questionnaires sent to all sheep breeders belonging to the `Associaça~o Paulista de Criadores de Ovinos' (ASPACO; Sa~o Paulo State Association of Sheep Breeders). Response reliability was tested by means of random visits paid to 10.6% of the respondents. Most of the properties (89.5%) reported the presence of one or more ectoparasites. Screw-worm (Cochliomyia hominivorax) was the most frequent ectoparasite (72.5%), followed by bot fly larvae (Dermatobia hominis, 45.0%), ticks (Amblyomma cajennense) and Boophilus microplus, 31.3%) and finally lice (Damalinia ovis, 13.8%). Combined infestations also occurred, the most common one being screw-worm with bot fly larvae (36.0%) followed by bot fly larvae with ticks (13.9%), screw-worm with ticks (9.3%), bot fly larvae with lice (6.9%), and ticks with lice (5.0%). The most common triple combination was screw-worm, bot fly larvae and ticks (12.8%). Breeds raised for meat or wool were attacked by bot fly larvae and ticks more often than other breeds. Lice were only absent from animals of indigenous breeds. The relationships among these ectoparasites are discussed in terms of sheep breeds, flock size, seasonality and the ectoparasitic combinations on the host.  相似文献   

17.
Our particular attention in this article was given to natural mediators for macrophages isolated from the sites of tissue injury. A number of chemotactic factors, which may satisfy many criteria making them acceptable as inflammatory leucocyte chemotactic factors, has been separated. Among them, our laboratory has isolated three macrophage (monocyte) chemotactic factors (MCF-a, -b and -c). Their purification, characterization and functional specificity are discussed.  相似文献   

18.
19.
An experiment was conducted to study disappearance of C14 to C18 fatty acids, lag times and biohydrogenation (BH) rates of C18 fatty acids of ground soya bean and canola seeds in situ. Three ruminally fistulated Dallagh sheep were used to determine ruminal BH of unsaturated fatty acids (UFAs). Differences in the disappearance of fatty acids through the bags and lag times were observed between the oilseeds. We saw that the longer the incubation time of the oilseeds in the rumen, the lower the content of C18:2 and C18:3. Significantly higher lag times for both C18:2 and C18:3 were observed in ground canola compared to ground soya bean. BH rates of C18:2 and C18:3 fatty acids in soya bean were three times higher than those of canola. These results suggest that the fatty acid profile of fat source can affect the BH of UFAs by rumen micro‐organisms. So that UFAs of canola had higher ability to escape from ruminal BH. It seems that fatty acid profile of ruminant products is more affected by canola seed compared to soya bean seed.  相似文献   

20.
Serum biochemical values and the wet weight to dry weight ratios of tissues were determined in yaks in Shandan county of Gansu province. The liver, kidney, heart and muscle contents of seven elements in yaks were also analysed. Most serum biochemical values were similar to those of cattle, camels and sheep, but the calcium concentration was considerably above the normal range for other ruminants. The liver contained the highest concentrations of copper, manganese and cobalt and the kidney of selenium, iron and calcium.Abbreviations Alb albumin - ALT alanine aminotransferase - AST aspartate aminotransferase - BUN blood urea nitrogen - Chol cholesterol - Glob globulin - -GT -glutamyl transpeptidase - IP inorganic phosphorus - TP total protein  相似文献   

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