Clinical Investigations in a Goat Herd with Outbreaks of Listeriosis     

Torleiu Lken  Hallstein Grnstl 《Acta veterinaria Scandinavica》1982,23(3):380

The majority of 50 nonpregnant dairy goats in a herd showed acute symptoms of disease for 1–2 days after a sudden change in weather conditions, feeding regime and management. In 17 of the does the condition progressed with symptoms of septicaemia with depression, fever, inappetence and hypogalactia for a period of up to 5 weeks. Only 1 of these 17 animals died. Three weeks after the first symptoms were seen, 7 other animals showed typical symptoms of listeric encephalitis. All but 1 recovered within 2 weeks. Treatment with penicillin seemed to have good effect against both these disease forms.The does with symptoms of septicaemia had significantly higher antibody titres against Listeria monocytogenes than the animals with encephalitis and the remainder.  相似文献   

Effects of dietary supplementation of a purified nucleotide mixture on immune function and disease and stress resistance in channel catfish,Ictalurus punctatus     

Thomas L Welker  Chhorn Lim  Mediha Yildirim‐Aksoy  Phillip H Klesius 《Aquaculture Research》2011,42(12):1878-1889

Juvenile channel catfish (14.4 g average initial weight) were fed diets supplemented with a purified nucleotide mixture for 8 weeks. The mixture consisted of five nucleotides supplied on an equal basis as disodium salts at combined concentrations of 0 (control), 0.1%, 0.3%, 0.9% or 2.7% of diet. Addition of nucleotides to diet produced a dose‐dependent reduction in survival of channel catfish to Edwardsiella ictaluri. Although the reasons are unclear, the high levels of nucleotides supplemented in this study may have contributed to the decrease in disease resistance, and this decrease appeared to be unrelated to the innate immune (unaffected) and specific antibody (enhanced) responses. Stress resistance increased with a corresponding amelioration of the immunosuppressive effects of the stress response on non‐specific immunity (lysozyme and bactericidal activity) as nucleotides increased in diet. Use of exogenous nucleotides as a prophylactic treatment before culture‐related stress exposure may prove beneficial by decreasing the immunosuppressive effects of stress but not in prevention of ESC.  相似文献   

尼罗罗非鱼致病性嗜水气单胞菌的分离鉴定与药敏试验   总被引：1，自引：0，他引：1  

董忠典  周芬娜  袁颜颜  冯艳艳  王慧 《东北农业大学学报》2012,43(6):110-115

从自然患病的尼罗罗非鱼(Oreochromis niloticus)肝脏组织分离出2株细菌,命名为M-O1和M-02。用M-O1和M-02分别在实验室人工感染健康的尼罗罗非鱼,被感染鱼3周内全部死亡,且患病症状与自然发病症状一致。从被感染的鱼体中分离得到2株类似细菌(分别命名为W-01、W-02),说明分离的菌株为本次尼罗罗非鱼出血性败血症的病原菌。通过生理生化方法进行种属鉴定,确认以上分离到的4株细菌均为嗜水气单胞菌(Aeromonaz hydrophila),分别命名为M-O1、M-02、W-01、W-02。用19种常见药物对上述菌株进行药敏试验,4菌株对丁胺卡那、氟哌酸、庆大霉素、链霉素、恩诺沙星、新霉素、氟罗沙星和复方新诺明极为敏感;对氧哌嗪青霉素、利福平、麦迪霉素、红霉素、罗红霉素和阿奇霉素敏感,对羧苄青霉素、头孢噻吩、先锋霉素、氨苄青霉素和林可霉素为不敏感。  相似文献   

Virus isolation vs RT‐PCR: which method is more successful in detecting VHSV and IHNV in fish tissue sampled under field conditions?   总被引：1，自引：0，他引：1  

Knüsel R  Bergmann SM  Einer-Jensen K  Casey J  Segner H  Wahli T 《Journal of fish diseases》2007,30(9):559-568

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Experimental infection studies demonstrate the high susceptibility of the salmonid, lake herring, Coregonus artedi (Le Sueur), to the Great Lakes strain of viral haemorrhagic septicaemia virus (genotype IVb)     

Weeks C  Kim R  Wolgamod M  Whelan G  Faisal M 《Journal of fish diseases》2011,34(11):887-891

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Viral haemorrhagic septicaemia virus in marine fish and its implications for fish farming--a review     

Skall HF  Olesen NJ  Mellergaard S 《Journal of fish diseases》2005,28(9):509-529

Viral haemorrhagic septicaemia virus (VHSV) has, in recent decades, been isolated from an increasing number of free-living marine fish species. So far, it has been isolated from at least 48 fish species from the northern hemisphere, including North America, Asia and Europe, and fifteen different species including herring, sprat, cod, Norway pout and flatfish from northern European waters. The high number of VHSV isolations from the Baltic Sea, Kattegat, Skagerrak, the North Sea and waters around Scotland indicate that the virus is endemic in these waters. The VHSV isolates originating from wild marine fish show no to low pathogenicity to rainbow trout and Atlantic salmon, although several are pathogenic for turbot. Marine VHSV isolates are so far serologically indistinguishable from freshwater isolates. Genotyping based on VHSV G- and N-genes reveals four groups indicating the geographical origin of the isolates, with one group representing traditional European freshwater isolates and isolates of north European marine origin, a second group of marine isolates from the Baltic Sea, a third group of isolates from the North Sea, and a group representing North American isolates. Examples of possible transfer of virus from free-living marine fish to farmed fish are discussed, as are measures to prevent introduction of VHSV from the marine environment to aquaculture.  相似文献   

A study of the susceptibility of Atlantic halibut,Hippoglossus hippoglossus (L.), to viral haemorrhagic septicaemia virus isolated from turbot,Scophthalmus maximus (L.)     

Bowden TJ 《Journal of fish diseases》2003,26(4):207-212

The susceptibility of Atlantic halibut, Hippoglossus hippoglossus (L.), to viral haemorrhagic septicaemia virus (VHSV) was tested. Juvenile halibut of approximately 5 g weight were subjected to challenge by intraperitoneal injection, cohabitation and immersion to a VHSV isolate from an outbreak of the disease in turbot, Scophthalmus maximus (L.). The intraperitoneal injection gave the highest mortality rate of 28% after 50 days. The cohabitee group suffered 19% mortality rate and the immersion group only 2%. Control groups included turbot exposed either by intraperitoneal injection or immersion which suffered mortality rates of 93 and 50%, respectively. The results suggest that halibut are markedly less susceptible to VHSV than turbot.  相似文献   

奶牛溶血性巴氏杆菌病研究   总被引：1，自引：0，他引：1  

刘华英  彭远义 《西南大学学报(自然科学版)》1995,17(6):553-556

本文研究了重庆地区奶牛中流行的一种急性败血性疾病，并确认病原为溶出血性巴氏杆菌Ａ生物型，可致奶牛急性败血型病和肺炎。其发病率和致死率分别为９％～４０％和２５％～５０％。病原菌的抗原与多杀性巴氏杆菌仅部分相同，交互免疫力弱，牛出败弱毒活菌苗和牛出败氢氧化铝甲醛苗接种，不能保护奶牛不受溶血性巴氏杆菌感染。  相似文献   

Bullous emphysema with haemorrhage in a premature foal     

B. Bezdekova  M. Skoric  M. Pekarkova  R. Kabes  E. Vavrouchova  O. Dobesova  K. Corley 《Equine Veterinary Education》2012,24(9):447-452

A Warmblood foal was admitted at one day of age because of prematurity and seizures. Clinical and clinical pathology abnormalities were consistent with prematurity and suspected hypoxic seizures that responded to anti‐convulsive therapy. The foal stabilised after several days of intensive care but then developed an airway infection. Thoracic radiographs showed multiple cavitary lesions and ultrasound examination suggested intra‐cavital haemorrhage. The foal went on to develop septicaemia and was subjected to euthanasia. Post mortem examination revealed multiple bullous emphysema with haemorrhage. This disorder should be considered in the differential diagnosis of foals having air‐fluid filled cavities on thoracic radiographs.  相似文献   

Development of neutralizing antibody responses in muskellunge, Esox masquinongy (Mitchill), experimentally exposed to viral haemorrhagic septicaemia virus (genotype IVb)     

Millard EV  Faisal M 《Journal of fish diseases》2012,35(1):11-18

A complement‐dependent 50% plaque neutralization test was used to assess the neutralizing antibody response in sera of muskellunge, Esox masquinongy, experimentally infected with viral haemorrhagic septicaemia virus (VHSV, genotype IVb) by immersion. Groups of muskellunge were challenged with varying concentrations of VHSV: Group 1 with 10² plaque‐forming units (pfu) mL^?1, Group 2 with 4 × 10³ pfu mL^?1, Group 3 with 10⁵ pfu mL^?1 and Group 4 with 0 pfu mL^?1. The fish were held at a temperature of 11 ± 1 °C and were sampled over a 20‐week period. Neutralizing antibodies were not detected in sera of any of the negative control fish throughout the study. Low neutralizing titres were detected in Groups 1–3 by 6 days post‐infection (p.i.). Neutralizing titres of <80 were not detected again until 3, 4 and 7 weeks p.i. for Groups 2, 3 and 1, respectively, with peak titres for those groups occurring 16, 11 and 17 weeks p.i., respectively. VHSV was detected in serum for up to 11 weeks p.i. Results of this study show that survivors can be detected by a serological technique, despite being virus negative. This may benefit the investigation of VHSV IVb distribution in the Great Lakes and the study of host immune responses to this emerging sublineage.  相似文献