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OBJECTIVE: To report the use of sodium nitroprusside to induce deliberate hypotension to reduce hemorrhage and facilitate surgical ligation of complicated patent ductus arteriosus (PDA) in dogs. STUDY DESIGN: Retrospective study. ANIMALS: Six dogs. METHODS: Hemorrhage occurred during surgical ligation of PDA in 5 dogs. Surgical dissection and isolation of the PDA were very difficult in a sixth dog that was considered to be at increased risk for ductus rupture. Sodium nitroprusside (5 to 25 microg/kg/min intravenously) was administered to these 6 dogs to induce hypotension to reduce blood loss and facilitate surgical ligation of the PDA. RESULTS: Sodium nitroprusside infusion reduced blood pressure (mean arterial pressure, 45 to 60 mm Hg) within 5 to 10 minutes and hemorrhage from the PDA, facilitating its surgical ligation. Recovery from surgery and anesthesia was uneventful in all 6 dogs. CONCLUSIONS: Sodium nitroprusside infusion can be used to induce deliberate hypotension in dogs to facilitate surgical ligation of PDA. CLINICAL RELEVANCE: Sodium nitroprusside infusion produces hypotension within 5 to 10 minutes and is easy to control, rapidly abates, and should help to facilitate surgical ligation of PDA.  相似文献   
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Summary Stepwise regression analyses provided an estimate of the net effect of yield components on lint yield of Upland cotton. Data from strain tests in the Pee Dee, South Carolina, cotton breeding program for crop years 1968 and 1969 were used in these analyses. Lint yield/m2 was the dependent variable. Independent variables were: bolls/m2, lint/seed, and seeds/boll.Correlation analyses indicated the relationships among yield components. Partial correlation coefficients were utilized to show the order of variable addition in the regression equations. We found that bolls/m2 assumes the major role in determining yield. The lint/seed component assmes the secondary role in the development of lint yield. Seeds/boll made a relatively larger total contribution only after lint/seed had made its contribution.These data indicate that selection pressure should be placed on prolificacy (bolls/m2) and seeds/boll, concommitantly with selection to maintain or increase lint/seed. Although the lint/seed component makes a relatively smaller total contribution to lint yield, it is necessary to maintain or increase this component to secure the increased contributions of seeds/boll.Cooperative investigations of the Plant Science Research Division, Agricultural Research Service, US Department of Agriculture and the Tennessee and South Carolina Agricultural Experiment Stations. South Carolina Technical Contribution No 954.  相似文献   
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Parathyroid carcinoma (PTC) is rare in dogs and there is little information documenting its treatment and prognosis. The objective of this study was to describe the outcome of dogs with PTC treated with surgical excision. Medical records of 19 dogs undergoing surgical excision of PTC between 1990 and 2010 were reviewed retrospectively. Dogs were presented for clinical hypercalcaemia or incidental hypercalcaemia noted by referring veterinarians on routine serum chemistry profiles. A parathyroid nodule was identified with cervical ultrasound in 17/17 dogs. Hypercalcaemia resolved in 18/19 dogs within 4 days postoperatively. Nine developed hypocalcaemia. None were confirmed to develop recurrent or metastatic PTC. The only death associated with PTC was a dog that was euthanized for intractable hypocalcaemia 9 days after surgery. Estimated 1-, 2- and 3-year survival rates were 72, 37 and 30%, respectively. Excision of PTC results in resolution of hypercalcaemia and excellent tumour control.  相似文献   
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