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1.
前  言马立克氏病(Marek’sDisease,MD)是由疱疹病毒引起的鸡淋巴细胞增生性肿瘤疾病。该病首次报道于1907年,其主要特征是病鸡的周围神经、性腺、各脏器、眼的虹膜、肌肉和皮肤的淋巴细胞浸润和形成肿瘤病灶。马立克氏病病毒最早由英国学者于1967年分离获得。本病主要发生于密集饲养的养鸡场,特别是肉仔鸡发生该病后损失严重。马立克氏病病毒还容易发生基因突变而增强毒力。不同品种的鸡对马立克氏病的易感性不同,采用马立克氏病疫苗可有效地控制该病的感染,但其免疫效果受许多因素的影响。要控制马立克氏病的发生,必须加…  相似文献   

2.
<正>马立克氏病(Marek′s disease,MD)是由鸡的马立克氏病病毒(Marek′s disease virus,MDV)引起的鸡的一种肿瘤性疾病,以淋巴细胞增生和肿瘤的形成为主要特征,以外周神经、生殖腺、脏器、免疫器官中单核细胞浸润以及由于外周神经肿瘤细胞的集聚而引起的半瘫痪或完全瘫痪为典型特征。匈牙利著名的兽医病理学家马立克在1907年首先报道了该病,英国科学家Biggs在1961年倡导开始使用马立克氏病这一名称[1]。上世纪二、三十年代,  相似文献   

3.
鸡马立克氏病(Marek′s Disease,MD)是由疱疹病毒引起的鸡淋巴细胞增生性肿瘤疾病,其病原为马立克氏病病毒(MDV)。该病主要特征是病鸡的外周神经、性腺、各种脏器、眼的虹膜、肌肉和皮肤等发生淋巴细胞浸润、肿大和形成肿瘤。本病  相似文献   

4.
<正>蛋鸡马立克氏病是由病毒引起的鸡的一种传染病,当其发生时,会对鸡群造成严重影响,虽然各种疫苗已经成熟并得到了广泛的应用,但该病仍然在部分地区时有发生,给养鸡业带来重大的经济损失。1病原体马立克氏病的病原体为马立克氏病毒,主要侵害鸡的外周神经、性腺、虹膜、皮肤和各内脏器官,病变部位发生淋巴细胞浸润和形成肿瘤灶,最终导致病鸡  相似文献   

5.
1马立克氏病由病毒引起的以淋巴细胞增生为特征的肿瘤性疾病。鸡对该病的易感性最强,特别是1日龄雏鸡最易感,随日龄的增长,其易感性逐渐减弱。鸡马立克氏病潜伏期较  相似文献   

6.
马立克氏病是鸡的一种传染性极强的B淋巴细胞增生性肿瘤疾病。该病从1907年最初报道至今已有一百年的历史,随着养殖集约化的程度的提高,鸡群饲养密度的加大,马立克氏病病毒毒力的不断增强,免疫失败现象普遍存在,导致马立克氏病流行严重,对养禽业造成严重经济损失。本文就马立克氏病免疫失败的原因作一概述,并探讨在我国推广鸡胚马立克氏病疫苗免疫接种的可行性。  相似文献   

7.
《兽医导刊》2012,(6):67-68
鸡马立克氏病(MD)是由马立克氏病毒(MDV)引起鸡的一种高度接触性的淋巴组织增生性肿瘤疫病,主要病理特征是各种内脏组织器官、外周神经、性腺、虹膜、肌肉和皮肤等组织器官的单核细胞浸润,产生淋巴细胞性肿瘤。该病于1907年首先由匈牙利兽医病理学家马立克  相似文献   

8.
鸡马立克氏病是由马立克氏病毒引起的,是鸡的一种常见的淋巴细胞增生性疾病。其特征是周神经、各种脏器、虹膜和皮肤等发生淋巴细胞浸润和形成肿瘤。鸡马立克氏病既是一种病毒性传染病,又是一种恶性肿瘤性疾病有高度的传染性,对养鸡业造成严重威胁。因此,本文主要从病原、流行病学特点、临床症状、病理学变化、诊断和防制6个方面对鸡马立克氏病进行综述,期望为鸡马立克氏病的防制奠定理论基础。  相似文献   

9.
<正>鸡马立克氏病是养鸡场非常常见的病毒性疾病之一,给养鸡业带来了严重危害。鸡马立克氏病是由疱疹病毒引起的具有高度传染性的疫病,主要特征是病鸡外虹膜、各脏器等组织发生淋巴细胞样浸润,是一种淋巴瘤性质的肿瘤疾病。严重危害养鸡业的健康发展,给养鸡业带来了巨大的经济损失。其中免疫接种是预防该病的关键之一,但是大多情况下免疫效果不理想,下面将其原因及防治对策进行分析。1鸡马立克氏病免疫效果不佳的原因  相似文献   

10.
鸡马立克氏病的诊断和预防   总被引:1,自引:0,他引:1  
鸡马立克氏病简称MD,是由疱疹病毒科中的马立克氏病疱疹病毒引起的最常见的鸡恶性肿瘤病(癌)。该病以淋巴细胞组织增生,在各内脏器官以及外周神经、肌肉、皮肤中产生单核细胞浸润和肿瘤为特征。有传染性,能导致鸡大批死亡,对养鸡业造成很大威胁,必须引起广大畜牧兽医工作者的高度重视。  相似文献   

11.
12.
采用高效液相色谱法测定癸氧喹酯干混悬剂的含量,在2-250μg/mL范围内,峰面积的常用对数与进样量浓度的常用对数呈良好的线性关系,R^2=1(n=5),平均回收率为99.24%~99.51%,RSD在0.05%~0.28%。此方法分析时间短,样品前处理简便、定量结果准确,重现性好,结果满意,为其质量控制提供了依据。  相似文献   

13.
在现代法律秩序中,商会自治规范是制定法的基础和必要的补充,甚至在某些方面替代了制定法;商会自治规范主要包括商会组织规范、行为规范、惩罚规范以及争端解决规范等;其效力仅及于其内部成员;商会自治规范和制定法之间存在冲突,但也存在整合的基础。  相似文献   

14.
本文概述了猪的毛色类型、猪的毛色遗传模式,着重综述了猪毛色基因分子基础的研究进展,指出存在问题并就未来发展方向做了思考。  相似文献   

15.
为贯彻落实《兽药生产质量管理规范》(简称《兽药GMP》),进一步推动兽药GMP实施进程,我部制定了《兽药生产质量管理规范检查验收办法》,现予公告。本公告自2003年6月1日起施行。附件:兽药生产质量管理规范检查验收办法二○○三年四月十日第一章 总则 第一条 为推动《兽药生产质量管理规范》(以下简称兽药GMP)的实施,规范兽药GMP检查验收工作,制定本办法。 第二条 农业部负责全国兽药GMP管理和检查验收工作;负责制修订兽药GMP检查验收管理规定;负责兽药GMP检查员队伍建设和监督管理工作,负责国际兽药贸易中GMP互认工作。 …  相似文献   

16.
以国际标准强毒R株人工感染非免疫产蛋鸡,定时扑杀,分别从鼻窦、眶下孔、气管、肺、气囊、卵巢和输卵管分离MG,并收集感染鸡所产蛋分离MG。结果表明,人工感染48小时后上、下呼吸道及肺已被全面感染,96小时气囊已被感染,120小时输卵管已能分离到MG,卵巢始终分离不到MG。人工感染鸡自144小时便能在其所产蛋中分离出MG。药物治疗能在72小时内消除感染,油乳剂苗则需24天后逐渐降低蛋内MG分离率,药物卵内注射、种蛋药浴、高温处理均能杀死卵内MG,但以研制的种蛋浸泡剂药浴效果为最好。  相似文献   

17.
REASONS FOR PERFORMING STUDY: Centesis of the bicipital bursa using an 8.9 cm long spinal needle has been reported but the alternative of employing a 3.8 cm long hypodermic needle requires validation. OBJECTIVE: To compare the efficacy of 2 different methods of centesis of the bicipital bursa and to evaluate the usefulness of ultrasonographic imaging to determine the location of solution administered when centesis of the bursa is attempted. METHODS: For Trial 1, 6 clinicians, who had no previous experience of centesis of the bicipital bursa, attempted to inject a solution composed of an aqueous radiopaque contrast medium and physiological saline solution (PSS) into the bicipital bursae of 2/12 horses using the previously described distal approach to inject one bursa and a proximal approach to inject the contralateral bursa. The bicipital tendon and bursa were examined ultrasonographically before and after injection; and both shoulders were examined radiographically to identify the location of the medium. In Trial 2, another 6 clinicians, also with no previous experience of centesis, repeated Trial 1, using 6 horses, but the radiopaque contrast medium was mixed with air instead of PSS. RESULTS: Accuracy of centesis using the proximal approach was 39% and that of the distal approach 28%. Ultrasonographic examination of the shoulder allowed the location of solution and air to be accurately predicted in all 12 shoulders examined. CONCLUSIONS: Clinicians who have had no previous experience performing centesis of the bicipital bursa are unlikely to be successful in centesis using either approach. Radiographic examination after injecting a radiopaque contrast medium may be necessary to assess the success of centesis especially if bursal fluid is not obtained during centesis. Injecting air along with the radiopaque contrast medium provides more accurate ultrasonographic confirmation of centesis and better radiographic definition than does injection without air.  相似文献   

18.
用硝酸和高氯酸消化蜂蜜,使硒游离出来,在微酸性环境下,硒和2,3-二氨基萘(DAN)生成有较强荧光的物质,用环己烷萃取,在激发波长378nm,荧光波长518nm处测定其荧光强度。蜂蜜中硒含量范围:0.10~0.82μg/g。表明:蜂蜜应视为天然富硒营养品。  相似文献   

19.
乳酸杆菌益生作用机制的研究进展   总被引:2,自引:0,他引:2  
乳酸杆菌作为益生菌广泛用于人和动物。本文综述了乳酸杆菌改善宿主健康的机制。乳酸杆菌可通过产生抗菌物质如乳酸、过氧化氢、细菌素,或者通过竞争营养或肠道黏附位点来抑制致病菌;通过诱导黏附素的分泌或阻止细胞凋亡而增强肠道的屏障功能,从而保护肠道。文章重点讨论了乳酸杆菌表面成分(表面蛋白、脂磷壁酸和肽聚糖)与肠道受体(C型凝集素受体、Toll样受体和 Nod样受体),阐述了他们结合后启动免疫调节信号,调控肠道免疫功能以发挥改善健康作用的机制。  相似文献   

20.
Ingestively masticated fragments were collected and sized via sieving. Different sizes of esophageal masticate and ruminal digesta fragments, and ground fragments of larger masticated pieces were incubated in vitro, and undigested NDF remaining at intervals of up to 168 h of incubation was determined. The ruminal age-dependent time delay (tau) for onset of digestion of NDF was positively correlated (P < 0.004) with the mean sieve aperture estimated to retain 50% of the fragments between successive sieve apertures (MRA). Degradation rate of potentially degradable NDF (PDF) and level of indigestible NDF were not related (P > 0.10) to MRA of masticated and ground fragments. Estimates of tau were positively related to MRA, with slopes of bermudagrass < corn silage < ruminal fragments of corn silage. It was concluded that fragment size-, and consequently, ruminal age-dependent onset of PDF degradation of a mixture of different fragment sizes results in an age-dependent rate of degradation of the more rapidly degrading of two subentities of PDF. Models are proposed that assume a tau before onset of simultaneous degradation of PDF from two pools characterized as having gamma-modeled age-dependency and age-constant rates. The ruminal age-dependent pool seems to be associated with the faster-degrading pool, and its rate parameter increases with range in MRA in the population of fragments. Conceptually, the ruminal age-dependent rate parameter for PDF degradation seems to represent a composite of several effects: 1) effects of the size-dependent tau; 2) range in MRA of the population of ingestively masticated fragments; and 3) subentities of PDF that degrade via more rapid age-dependent rates compared with subentities of PDF that degrade via age-constant rates. The estimated fractional rates of ruminative comminution of ingestively masticated fragments (0.060 to 0.075/h) were of a magnitude similar to the mean fractional rates of PDF digestion (0.030 to 0.085/h), which implies that ruminative comminution may be first-limiting to fractional rate of PDF digestion. The in vivo roles of ingestive and ruminative mastication of fragments on PDF degradation must be considered in any kinetic system for estimating PDF digestion in the rumen. These results and others in the literature suggest that the rate of surface area exposure rather than intrinsic chemical attributes of PDF may be first-limiting to degradation rate of PDF in vivo.  相似文献   

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