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随着经济的发展,奶牛业也逐渐发展起来,但奶牛乳腺炎仍然是危害奶牛业的一大疾病,给奶牛生产带来严重的经济损失。盐酸克林霉素自70年代上市以来已20多年,其抗菌活性强,抗菌谱广,对革兰氏阳性菌具有明显抗菌活性。对衣原体、霉形体、恶性疟原虫和弓形虫都有杀灭作用。我们用青链霉素、阿莫西林、恩诺沙星、庆大霉素与盐酸克林霉素进行对比,治疗试验,探讨盐酸克林霉素对奶牛乳腺炎的治疗效果,为其在家畜疫病防治中推广应用打下基础。1材料与方法1.1药品与试剂盐酸克林霉素注射液为浙江大飞龙动物保健品有限公司生产克林美注射液(浙兽药字2002… 相似文献
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正利高霉素,兽药名称(通用名):盐酸大观-林可霉素可溶性粉。白色或类白色粉末。主要成份:盐酸大观霉素20%、盐酸林可霉素10%、粘杆菌素5%、臭乙新、布洛芬、免疫增效剂。一、药理作用本品为复方广谱抗菌类药,主要对G+菌和G-菌及支原体均有强力高效的抑制或杀灭作用。盐酸大观霉素与盐酸林可霉素联合应用再辅以特异活性因子,采用现代螯合工艺合成,其抗菌谱和活性比单方制剂显著扩大和增强。主要用于防 相似文献
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盐酸林可霉素和硫酸大观霉素及其复方的体外抗菌试验 总被引：3，自引：0，他引：3
选取 2 0种临床常见畜禽病原微生物 ,观察其对盐酸林可霉素、硫酸大观霉素、盐酸林可霉素和硫酸大观霉素复方以及对照药物青霉素的敏感性。其结果为 :盐酸林可霉素、硫酸大观霉素、盐酸林可霉素和硫酸大观霉素、青霉素对2 0种病原微生物的最小抑菌浓度 (MIC)分别是0 .0 6～ 2 56,0 .98～ 2 56,0 .1 3 / 0 .2 6～ 3 2 / 64μg/m L和 0 .0 6～ 2 56μg/ m L。 相似文献
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肺炎链球菌又称肺炎球菌为链球菌属一员,主要寄生在人和动物的呼吸道中,猪肺炎链球菌病的主要症状为幼畜出现败血症和大叶性肺炎及脑膜炎等;在临床诊断中发现疑似病例,并在实验室诊断中分离到一株疑似菌株,经形态学、生化及分子鉴定确定为肺炎链球菌;药敏试验结果为病原菌对头孢噻呋、左氧氟沙星、杆菌肽、阿米卡星高度敏感,对甲氧苄啶、卡那霉素、甲砜霉素、盐酸克林霉素、盐酸林可霉素、庆大霉素不敏感。 相似文献
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林可霉素与大观霉素配伍（简称林＋大合剂），在抗菌谱上两者可互补，在抗菌机理上有协同抗菌作用。对革兰氏阴性菌、革兰氏阳性菌、支原体、猪痢疾密螺旋体等致病菌有极强的抗菌活性，也是促生长、防治肠道疾病和呼吸系统疾病的药物添加剂，具有流动性好的理化特性和添加成本低、性价比高的优点。目前抗菌促生长类饲料添加剂种类很多，但林可霉素与大观霉素在断奶仔猪日粮中的组合应用的报道较少。本试验探讨林可霉素与大观霉素配伍对断奶仔猪生长性能和腹泻率的影响，为其在养猪生产中的应用提供科学依据。 相似文献
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以广西柳州市某猪场爆发猪喘气病为对象,用赛林注射液（盐酸大观霉素盐酸林可霉素）、盐酸大观霉素注射液、盐酸林可霉素注射液进行对比治疗。结果表明,赛林组的高、中、低剂量治疗猪喘气病总有效率分别为95%、95%、90%;与盐酸林可霉素组的总有效率85%相比,差异显著（P〈0.05）;与盐酸大观霉素组的总有效率35%相比,差异极显著（P〈0.01）。 相似文献
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克林霉素于1966年由Magerlein等以氯离子取代林可霉素分子中第7位的羟基首次合成。作用于细菌核糖体的50s亚单位而抑制菌体蛋白合成,通过抑制肽链的延长而抑制细菌蛋白质的合成,从而清除细菌表面A蛋白质和绒毛状外衣,使其易被吞噬和杀灭。对机体免疫系统有增强免疫调节作用,增强多型核白细胞的吞噬和杀菌功能,改变细菌表面活性和抑制细菌毒素的产生。抗菌活性强,抗菌谱广,对革兰阳性菌具有明显抗菌活性。对衣原体、霉形体、恶性疟原虫和弓形虫都有杀灭作用。为给兽医临床提供用药依据,试验进行了奶牛急性乳腺炎病原菌的分离培养和鉴定,克林… 相似文献
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为筛选出治疗奶牛临床型乳房炎更好的方法,本试验将患病牛分为A、B两组,A组采取盐酸克林霉素和乳酸甲氧苄啶治疗,B组采取青霉素、链霉素治疗。结果显示:用克林霉素和乳酸甲氧苄啶治疗的A组9例乳房炎病牛的疗效显著,用青霉素和链霉素治疗的B组9例病牛的疗效逊于A组。由此可见,在治疗奶牛临床型乳房炎时,应用盐酸克林霉素加上抗菌增效剂乳酸甲氧苄啶的治疗方法是非常有效的,尤其是针对反复发作的顽固性乳房炎,该方法可以在治疗奶牛临床型乳房炎时广泛应用。 相似文献
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用赛林注射液(盐酸大观霉素、盐酸林可霉素)、盐酸大观霉素注射液、盐酸林可霉素注射液进行猪气喘病对比治疗。结果:赛林组(高、中、低剂量)治疗猪气喘病总有效率为93.3%,与盐酸林可霉素组有效率85%相比较,差异显著(P0.05);与盐酸大观霉素组有效率35%相比较,差异极显著(P0.01)。试验表明,赛林注射液治疗猪气喘病疗效确实。 相似文献
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魏静 《四川畜牧兽医学院学报》2009,(4):28-32
在现代法律秩序中,商会自治规范是制定法的基础和必要的补充,甚至在某些方面替代了制定法;商会自治规范主要包括商会组织规范、行为规范、惩罚规范以及争端解决规范等;其效力仅及于其内部成员;商会自治规范和制定法之间存在冲突,但也存在整合的基础。 相似文献
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本文概述了猪的毛色类型、猪的毛色遗传模式,着重综述了猪毛色基因分子基础的研究进展,指出存在问题并就未来发展方向做了思考。 相似文献
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以国际标准强毒Ｒ株人工感染非免疫产蛋鸡,定时扑杀,分别从鼻窦、眶下孔、气管、肺、气囊、卵巢和输卵管分离ＭＧ,并收集感染鸡所产蛋分离ＭＧ。结果表明,人工感染４８小时后上、下呼吸道及肺已被全面感染,９６小时气囊已被感染,１２０小时输卵管已能分离到ＭＧ,卵巢始终分离不到ＭＧ。人工感染鸡自１４４小时便能在其所产蛋中分离出ＭＧ。药物治疗能在７２小时内消除感染,油乳剂苗则需２４天后逐渐降低蛋内ＭＧ分离率,药物卵内注射、种蛋药浴、高温处理均能杀死卵内ＭＧ,但以研制的种蛋浸泡剂药浴效果为最好。 相似文献
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REASONS FOR PERFORMING STUDY: Centesis of the bicipital bursa using an 8.9 cm long spinal needle has been reported but the alternative of employing a 3.8 cm long hypodermic needle requires validation. OBJECTIVE: To compare the efficacy of 2 different methods of centesis of the bicipital bursa and to evaluate the usefulness of ultrasonographic imaging to determine the location of solution administered when centesis of the bursa is attempted. METHODS: For Trial 1, 6 clinicians, who had no previous experience of centesis of the bicipital bursa, attempted to inject a solution composed of an aqueous radiopaque contrast medium and physiological saline solution (PSS) into the bicipital bursae of 2/12 horses using the previously described distal approach to inject one bursa and a proximal approach to inject the contralateral bursa. The bicipital tendon and bursa were examined ultrasonographically before and after injection; and both shoulders were examined radiographically to identify the location of the medium. In Trial 2, another 6 clinicians, also with no previous experience of centesis, repeated Trial 1, using 6 horses, but the radiopaque contrast medium was mixed with air instead of PSS. RESULTS: Accuracy of centesis using the proximal approach was 39% and that of the distal approach 28%. Ultrasonographic examination of the shoulder allowed the location of solution and air to be accurately predicted in all 12 shoulders examined. CONCLUSIONS: Clinicians who have had no previous experience performing centesis of the bicipital bursa are unlikely to be successful in centesis using either approach. Radiographic examination after injecting a radiopaque contrast medium may be necessary to assess the success of centesis especially if bursal fluid is not obtained during centesis. Injecting air along with the radiopaque contrast medium provides more accurate ultrasonographic confirmation of centesis and better radiographic definition than does injection without air. 相似文献
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Effects of size of ingestively masticated fragments of plant tissues on kinetics of digestion of NDF
Ingestively masticated fragments were collected and sized via sieving. Different sizes of esophageal masticate and ruminal digesta fragments, and ground fragments of larger masticated pieces were incubated in vitro, and undigested NDF remaining at intervals of up to 168 h of incubation was determined. The ruminal age-dependent time delay (tau) for onset of digestion of NDF was positively correlated (P < 0.004) with the mean sieve aperture estimated to retain 50% of the fragments between successive sieve apertures (MRA). Degradation rate of potentially degradable NDF (PDF) and level of indigestible NDF were not related (P > 0.10) to MRA of masticated and ground fragments. Estimates of tau were positively related to MRA, with slopes of bermudagrass < corn silage < ruminal fragments of corn silage. It was concluded that fragment size-, and consequently, ruminal age-dependent onset of PDF degradation of a mixture of different fragment sizes results in an age-dependent rate of degradation of the more rapidly degrading of two subentities of PDF. Models are proposed that assume a tau before onset of simultaneous degradation of PDF from two pools characterized as having gamma-modeled age-dependency and age-constant rates. The ruminal age-dependent pool seems to be associated with the faster-degrading pool, and its rate parameter increases with range in MRA in the population of fragments. Conceptually, the ruminal age-dependent rate parameter for PDF degradation seems to represent a composite of several effects: 1) effects of the size-dependent tau; 2) range in MRA of the population of ingestively masticated fragments; and 3) subentities of PDF that degrade via more rapid age-dependent rates compared with subentities of PDF that degrade via age-constant rates. The estimated fractional rates of ruminative comminution of ingestively masticated fragments (0.060 to 0.075/h) were of a magnitude similar to the mean fractional rates of PDF digestion (0.030 to 0.085/h), which implies that ruminative comminution may be first-limiting to fractional rate of PDF digestion. The in vivo roles of ingestive and ruminative mastication of fragments on PDF degradation must be considered in any kinetic system for estimating PDF digestion in the rumen. These results and others in the literature suggest that the rate of surface area exposure rather than intrinsic chemical attributes of PDF may be first-limiting to degradation rate of PDF in vivo. 相似文献