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左旋咪唑对鸡传染性法氏囊病疫苗免疫效果影响的观察 总被引：4，自引：0，他引：4
为观察左旋咪唑对鸡传染性法氏囊病疫苗免疫效果的影响，进行2个实验：试验1，饮水给予10mg/kg.d左旋咪唑，连用3d，然后进行鸡传染性法氏囊病疫苗初次免疫，免疫后14－21d，鸡血清抗IBDV抗体滴度明显降低；试验2，鸡在初次免疫后35d进行第2次免疫，且在2次免疫前先应用10mg/kg.d左旋咪唑，连用3d，免疫后鸡血清抗IBDV抗体滴度无明显变化。 相似文献
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本研究观察了药物对传染性法氏囊病（IBD）活疫苗初次免疫和二次免疫的影响，结果显示高抗传染性法氏囊病病毒（IBDV）母源抗体雏鸡IBD活疫苗初次免疫前应用10－100毫克／千克甲硝唑和10毫克／千克左旋咪唑，在免疫鸡血清抗IBDV抗体水平明显下降，甲硝唑用药鸡疫苗二次免疫后，血清抗IBDV抗体滴度明显高于未用药对照组。10毫克／千克左旋咪唑给药组疫苗二次免疫后鸡血清抗IBDV抗体滴度与未用药对照组无明显差别。 相似文献
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西咪替丁对鸡新城疫疫苗免疫效果的影响 总被引：4，自引：0，他引：4
进行了两个实验：实验一观察药物对鸡ND疫苗初次免疫的影响，结果显示7日龄高母源抗体（9.36log2)雏鸡免疫ND活疫苗前用药，10mg/kg西咪替丁用药鸡免疫后7－14d,100mg/kg西咪替丁用药鸡免疫后7－28d，抗体滴度明显升高；10mg/kg左旋咪唑用药鸡免疫后7－21d，抗体滴度与未用药对照组无明显差别，但28d抗体滴度明显高于未用药对照组。免疫后用药，10mg/kg西咪替丁用药后7d，抗体滴度明显高于空白对照组；用药后14d，各用药组抗体滴度与空白对照组无明显差别；用药后21d,10,100mg/kg西咪替丁和10mg/kg左旋咪唑用药鸡抗体滴度均明显高于空白对照组。实验二观察药物对ND疫苗二次免疫的影响，结果显示10，100mg/kg西咪替丁用药ND疫苗二次免疫后7－28d，鸡血清抗NDV抗体滴度明显高于未用药对照组。10mg/kg左旋咪唑用药组，疫苗二次免疫后7－28d，抗体滴度也明显升高。 相似文献
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进行了两个实验:实验一观察药物对鸡ND疫苗初次免疫的影响,结果显示7日龄高母源抗体(9.36log2)雏鸡免疫ND活疫苗前用药,10mg/kg西咪替丁用药鸡免疫后7～14d、100mg/kg西咪替丁用药鸡免疫后7～28d,抗体滴度明显升高;10mg/kg左旋咪唑用药鸡免疫后7～21d,抗体滴度与未用药对照组无明显差别,但28d抗体滴度明显高于未用药对照组。免疫后用药,10mg/kg西咪替丁用药后7d,抗体滴度明显高于空白对照组;用药后14d,各用药组抗体滴度与空白对照组无明显差别;用药后21d,10、100mg/kg西咪替丁和10mg/kg左旋咪唑用药鸡抗体滴度均明显高于空白对照组。实验二观察药物对ND疫苗二次免疫的影响,结果显示10、100mg/kg西咪替丁用药ND疫苗二次免疫后7～28d,鸡血清抗NDV抗体滴度明显高于未用药对照组。10mg/kg左旋咪唑用药组,疫苗二次免疫后7～28d,抗体滴度也明显升高。 相似文献
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左旋咪唑增强鸡新城疫疫苗免疫效果的观察 总被引：3，自引：0，他引：3
本文报道了左旋咪唑对鸡新城疫病疫苗免疫效果的影响。进行了两个实验：每个实验分为10毫克／千克，左旋咪唑给药组和空白对照组。实验一观察对鸡ND疫苗初次免疫的影响：疫苗免疫前用药，5日龄时给药，连用3天，7日龄滴鼻给予ND－Lasota系疫苗；疫苗免疫后用药，7日龄时滴鼻给予ND－Lasota系活疫苗，13日龄时给药，连用3天。实验二观察对鸡ND疫苗二次免疫的影响：7日龄时饮水给予ND＋IBD联活疫苗，40日龄时给药，连用3天，42日龄时肌肉注射ND－Lasota系疫苗。实验一结果显示，免疫前用药，10mg/kg左旋咪唑用药组，首次免疫后7－21d，抗体滴度与未用药对照组比较无明显差别，但28d抗体滴度明显高于未用药对照组；免疫后用药，用药后21d,10mg/kg左旋咪唑用药组，抗体滴度明显高于空白对照组。实验二结果显示10mg/kg左旋咪唑用药组，疫苗二次免疫后7－28d，抗体滴度明显高于未用药对照组。 相似文献
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本文报道了左旋咪唑对鸡新城疫病疫苗免疫效果的影响。进行了两个实验:每个实验分为10毫克/千克,左旋咪唑给药组和空白对照组。实验一观察对鸡ND疫苗初次免疫的影响:疫苗免疫前用药,5日龄时给药,连用3天,7日龄滴鼻给予ND—Lasota系疫苗;疫苗免疫后用药,7日龄时滴鼻给予ND—Lasota系活疫苗,13日龄时给药,连用3天。实验二观察对鸡ND疫苗二次免疫的影响:7日龄时饮水给予ND+IBD二联活疫苗,40日龄时给药,连用3天,42日龄时肌肉注射ND—Lasota系疫苗。实验一结果显示,免疫前用药,10mg/kg左旋咪唑用药组,首次免疫后7～21d,抗体滴度与未用药对照组比较无明显差别,但28d抗体滴度明显高于未用药对照组;免疫后用药,用药后21d,10mg/kg左旋咪唑用药组,抗体滴度明显高于空白对照组。实验二结果显示10mg/kg左旋咪唑用药组,疫苗二次免疫后7～28d,抗体滴度明显高于未用药对照组。 相似文献
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左旋咪唑对鸡细胞免疫和体液免疫功能的作用 总被引：40，自引：2，他引：38
系统研究了左旋咪唑对鸡细胞免疫和体液免疫功能的作用。结果表明左旋咪唑可影响正常鸡的免疫功能 :左旋咪唑可显著促进鸡外周血T淋巴细胞增殖 ,但对B淋巴细胞无明显影响 :2 5～ 1 0mg/kg左旋咪唑可使CD+4/CD+8淋巴细胞比值明显升高 ;左旋咪唑可使鸡体内抗颗粒性、胸腺依赖性抗原SRBC抗体滴度 ,抗可溶性、胸腺依赖性抗原BSA抗体滴度和抗非胸腺依赖性抗原BA抗体滴度均明显升高 ;2 5～ 1 0mg/kg左旋咪唑可使鸡血清总补体活性明显升高。左旋咪唑影响正常鸡回忆性免疫应答反应 :左旋咪唑 ( 1 0mg/kg)可使二次免疫鸡抗SRBC抗体滴度和抗BA抗体滴度回忆性免疫应答反应明显升高 ;但使鸡对抗BSA抗体滴度回忆性免疫应答反应明显降低。 相似文献
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甲哨唑对鸡细胞免疫和体液免疫功能的作用 总被引：3，自引：0，他引：3
本试验观察了甲硝唑对鸡细胞免疫和体液免疫功能的作用，并与左旋咪唑进行了比较。结果表明2．5－400mg/kg甲哨唑可显著促进鸡外周血T淋巴细胞增殖，但对B淋巴细胞无明显影响；可使CD4^ /CD8^ 淋巴细胞比值明显升高；可使鸡外周血淋巴细胞诱生IL－2活性明显增强；可使鸡体内抗颗粒性胸腺依赖性抗原SRBC抗体滴度、抗可溶性胸腺依赖性抗原BSA抗体滴度和抗非胸腺依赖性抗原BA抗体滴度明显升高；可使鸡血清总补体活性明显升高。与甲硝唑比较，左旋咪唑也存在着非常类似的作用，2．5－10mg/kg左旋咪唑可明显促进外周血T淋巴细胞增殖，可使CD4^ /CD8^ 淋巴细胞比值明显升高；可使鸡外周血淋巴细胞诱生IL－2活性明显增强；可使鸡体内抗SRBC抗体滴度、抗BSA抗体滴度和抗BA抗体滴度均明显升高；10mg/kg左旋咪唑甲硝唑可使血清补体总活性升高。上述结果表明甲硝唑和左旋咪唑两种咪唑类化合物在促进鸡细胞免疫和体液免疫可能存在着相似的作用机制。 相似文献
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魏静 《四川畜牧兽医学院学报》2009,(4):28-32
在现代法律秩序中,商会自治规范是制定法的基础和必要的补充,甚至在某些方面替代了制定法;商会自治规范主要包括商会组织规范、行为规范、惩罚规范以及争端解决规范等;其效力仅及于其内部成员;商会自治规范和制定法之间存在冲突,但也存在整合的基础。 相似文献
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本文概述了猪的毛色类型、猪的毛色遗传模式,着重综述了猪毛色基因分子基础的研究进展,指出存在问题并就未来发展方向做了思考。 相似文献
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以国际标准强毒Ｒ株人工感染非免疫产蛋鸡,定时扑杀,分别从鼻窦、眶下孔、气管、肺、气囊、卵巢和输卵管分离ＭＧ,并收集感染鸡所产蛋分离ＭＧ。结果表明,人工感染４８小时后上、下呼吸道及肺已被全面感染,９６小时气囊已被感染,１２０小时输卵管已能分离到ＭＧ,卵巢始终分离不到ＭＧ。人工感染鸡自１４４小时便能在其所产蛋中分离出ＭＧ。药物治疗能在７２小时内消除感染,油乳剂苗则需２４天后逐渐降低蛋内ＭＧ分离率,药物卵内注射、种蛋药浴、高温处理均能杀死卵内ＭＧ,但以研制的种蛋浸泡剂药浴效果为最好。 相似文献
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REASONS FOR PERFORMING STUDY: Centesis of the bicipital bursa using an 8.9 cm long spinal needle has been reported but the alternative of employing a 3.8 cm long hypodermic needle requires validation. OBJECTIVE: To compare the efficacy of 2 different methods of centesis of the bicipital bursa and to evaluate the usefulness of ultrasonographic imaging to determine the location of solution administered when centesis of the bursa is attempted. METHODS: For Trial 1, 6 clinicians, who had no previous experience of centesis of the bicipital bursa, attempted to inject a solution composed of an aqueous radiopaque contrast medium and physiological saline solution (PSS) into the bicipital bursae of 2/12 horses using the previously described distal approach to inject one bursa and a proximal approach to inject the contralateral bursa. The bicipital tendon and bursa were examined ultrasonographically before and after injection; and both shoulders were examined radiographically to identify the location of the medium. In Trial 2, another 6 clinicians, also with no previous experience of centesis, repeated Trial 1, using 6 horses, but the radiopaque contrast medium was mixed with air instead of PSS. RESULTS: Accuracy of centesis using the proximal approach was 39% and that of the distal approach 28%. Ultrasonographic examination of the shoulder allowed the location of solution and air to be accurately predicted in all 12 shoulders examined. CONCLUSIONS: Clinicians who have had no previous experience performing centesis of the bicipital bursa are unlikely to be successful in centesis using either approach. Radiographic examination after injecting a radiopaque contrast medium may be necessary to assess the success of centesis especially if bursal fluid is not obtained during centesis. Injecting air along with the radiopaque contrast medium provides more accurate ultrasonographic confirmation of centesis and better radiographic definition than does injection without air. 相似文献
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Effects of size of ingestively masticated fragments of plant tissues on kinetics of digestion of NDF
Ingestively masticated fragments were collected and sized via sieving. Different sizes of esophageal masticate and ruminal digesta fragments, and ground fragments of larger masticated pieces were incubated in vitro, and undigested NDF remaining at intervals of up to 168 h of incubation was determined. The ruminal age-dependent time delay (tau) for onset of digestion of NDF was positively correlated (P < 0.004) with the mean sieve aperture estimated to retain 50% of the fragments between successive sieve apertures (MRA). Degradation rate of potentially degradable NDF (PDF) and level of indigestible NDF were not related (P > 0.10) to MRA of masticated and ground fragments. Estimates of tau were positively related to MRA, with slopes of bermudagrass < corn silage < ruminal fragments of corn silage. It was concluded that fragment size-, and consequently, ruminal age-dependent onset of PDF degradation of a mixture of different fragment sizes results in an age-dependent rate of degradation of the more rapidly degrading of two subentities of PDF. Models are proposed that assume a tau before onset of simultaneous degradation of PDF from two pools characterized as having gamma-modeled age-dependency and age-constant rates. The ruminal age-dependent pool seems to be associated with the faster-degrading pool, and its rate parameter increases with range in MRA in the population of fragments. Conceptually, the ruminal age-dependent rate parameter for PDF degradation seems to represent a composite of several effects: 1) effects of the size-dependent tau; 2) range in MRA of the population of ingestively masticated fragments; and 3) subentities of PDF that degrade via more rapid age-dependent rates compared with subentities of PDF that degrade via age-constant rates. The estimated fractional rates of ruminative comminution of ingestively masticated fragments (0.060 to 0.075/h) were of a magnitude similar to the mean fractional rates of PDF digestion (0.030 to 0.085/h), which implies that ruminative comminution may be first-limiting to fractional rate of PDF digestion. The in vivo roles of ingestive and ruminative mastication of fragments on PDF degradation must be considered in any kinetic system for estimating PDF digestion in the rumen. These results and others in the literature suggest that the rate of surface area exposure rather than intrinsic chemical attributes of PDF may be first-limiting to degradation rate of PDF in vivo. 相似文献